More than once I have talked my way into a job, even without the right experience. Does it always work? Can you always overcome lack of experience or skills in an interview just by having the right attitude or chemistry? No. Of course not.As nice as you are, jobs may require specific skills than are hard to imagine from the outside, even with a good job description. (And not all job descriptions are written well.) Also, while some hiring managers are more open, others are by-the-book sticklers — and there’s no way to know for sure.So when is it worth taking a chance? I’m glad you asked.